45 Results for "

Aralia elata (Miq.) Seem.

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "Aralia elata (Miq.) Seem." in MCE Product Catalog:

4
Parishin
Parishin
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4 Cited Publications
Art. -Nr.: HY-N2031
CAS. Nr.: 62499-28-9
Category:  

Other Terpenoids Gastrodia elata Bl. Orchidaceae Terpenoids Plants

Target:  

Others

Parishin is a phenolic glucoside isolated from Gastrodia elata. Parishin exhibits antiaging effects and extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway .
2
Araloside A
Araloside A
0 Images
2 Cited Publications
Art. -Nr.: HY-N2115
CAS. Nr.: 7518-22-1
Synonyms: Chikusetsusaponin IV
Category:  

Cardiovascular Disease Triterpenes other families Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Renin Apoptosis Bcl-2 Family Interleukin Related

Araloside A (Chikusetsusaponin IV), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A can inhibit cell proliferation and induce apoptosis. Araloside A suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis .
1
Parishin B
Parishin B
0 Images
1 Cited Publications
Art. -Nr.: HY-N2124
CAS. Nr.: 174972-79-3
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS)

Parishin B is a parishin metabolite that can be isolated from Gastrodia elata with antioxidant activity .
1
Calenduloside E
Calenduloside E
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1 Cited Publications
Art. -Nr.: HY-N6850
CAS. Nr.: 26020-14-4
Category:  

Triterpenes other families Terpenoids Other Diseases Aralia elata (Miq.) Seem. Plants Endogenous metabolite Disease Research Fields Araliaceae

Target:  

Apoptosis Pyroptosis AMPK Bcl-2 Family JAK STAT Calcium Channel Interleukin Related TNF Receptor SOD Reactive Oxygen Species (ROS) PPAR

Calenduloside E is a pentacyclic triterpenoid saponin that can be extracted from the bark and roots of Aralia ovata, and has anti-inflammatory and anti-apoptotic activities. Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion injury. Calenduloside E also improves non-alcoholic fatty liver disease by regulating heat shock-dependent pathways, and inhibits ROS mediated JAK1-STAT3 pathways to reduce cellular inflammatory responses .
1
N6-(4-Hydroxybenzyl)adenosine
N6-(4-Hydroxybenzyl)adenosine
0 Images
1 Cited Publications
Art. -Nr.: HY-18775
CAS. Nr.: 110505-75-4
Synonyms: Para-topolin riboside
Target:  

Nucleoside Transporters Adenosine Receptor P2Y Receptor

Forschungsgebiete:  

Neurological Disease

N6-(4-Hydroxybenzyl) adenosine (Para-topolin riboside) is an equilibrative nucleoside transporter 1 (ENT1) inhibitor and a selective agonist of adenosine A2a receptor (A2aR), and also exhibits activity against P2Y12 receptor. N6-(4-Hydroxybenzyl) adenosine reduces ethanol intake and preference, attenuates operant conditioning-induced ethanol place preference, decreases the value of ethanol-related rewards, and inhibits collagen-induced platelet aggregation. N6-(4-Hydroxybenzyl) adenosine can be used in studies related to alcohol use disorder .
TIS108
TIS108
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Art. -Nr.: HY-136403
CAS. Nr.: 1315459-30-3
Reinheit:  99.92%
Target:  

Phytohormone

Forschungsgebiete:  

Others

TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment .
Parishin E
Parishin E
0 Images
Art. -Nr.: HY-N2126
CAS. Nr.: 952068-57-4
Category:  

Gastrodia elata Bl. Orchidaceae Other Diseases Phenols Plants Disease Research Fields

Target:  

Others

Parishin E, a parishin derivative isolated from Gastrodia elata, may have antioxidant property .
Parishin C
Parishin C
0 Images
Art. -Nr.: HY-N2125
CAS. Nr.: 174972-80-6
Category:  

Gastrodia elata Bl. Orchidaceae Phenols Plants

Target:  

5-HT Receptor iGluR Caspase Interleukin Related TNF Receptor SOD NF-κB

Parishin C is a brain-penetrant major bioactive component found in Gastrodia elata Blume. Parishin C is a 5-HT1A receptor agonist with an EC50 of 34 nM. Parishin C has antipsychotic and neuroprotective effects. Parishin C protects against Aβ-induced long-term potentiation damage and NMDA receptor current impairment. Parishin C reduces oxidative stress, pro-inflammatory cytokine levels, caspase activity, brain water content, and cerebral infarct volume; increases antioxidant enzyme activity and BDNF levels; improves nerve function and histopathological brain damage. Parishin C attenuates phencyclidine-induced immobility time increases, sociability deficits, and visual recognition memory impairment. Parishin C can be used for the research of ischemic stroke, Alzheimer's disease, and schizophrenia-like psychosis .
Araliadiol
Araliadiol
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Art. -Nr.: HY-N2887
CAS. Nr.: 1354638-93-9
Category:  

Natural Products Aralia cordata Thunb. Plants Disease Research Fields Araliaceae Cancer

Target:  

Others

Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cells growth with an IC50 value of 6.41 μg/mL .
Araloside V
Araloside V
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Art. -Nr.: HY-N6970
CAS. Nr.: 340963-86-2
Synonyms: Congmunoside V
Category:  

Triterpenes Terpenoids Metabolic Disease Plants Disease Research Fields Araliaceae Aralia chinensis L.

Target:  

Others

Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata .
Araloside VII
Araloside VII
0 Images
Art. -Nr.: HY-N2002
CAS. Nr.: 340982-22-1
Synonyms: Congmunoside VII
Category:  

Other Terpenoids Terpenoids Other Diseases Plants Disease Research Fields Araliaceae Aralia chinensis L.

Target:  

Others

Araloside VII (Congmunoside VII) is a saponin isolated from leaves of Aralias elate .
Globulol
Globulol
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Art. -Nr.: HY-N8389
CAS. Nr.: 489-41-8
Category:  

Terpenoids Sesquiterpenes Myrtaceae Plants Eucalyptus globulus Labill.

Target:  

Bacterial Fungal PAK Akt STAT PD-1/PD-L1 Apoptosis CCR

Globulol is a terpenoid metabolite and Antimicrobial agent. Globulol can be isolated from Alpinia oxyphylla Miq. Globulol binds to PAK4, reduces the expression level of PAK4 in cancer cells, decreases the phosphorylation of AKT, and downregulates the expressions of STAT3, phosphorylated STAT3, and PD-L1. Globulol promotes the secretion of CCL4 by cancer cells. Globulol reduces the viability and proliferation ability of cancer cells, induces G0/G1 cell cycle arrest and Apoptosis in cancer cells, and inhibits cancer cell migration and the integrity of 3D tumor spheres. Globulol enhances the relevant effects of anti-PD-1 agents in the cancer cell microenvironment. Globulol exhibits anticancer activity against liver cancer. Globulol inhibits the mycelial growth of phytopathogenic fungi and the growth of phytopathogenic bacteria. Globulol can be used in studies related to hepatocellular carcinoma .
Araloside X
Araloside X
0 Images
Art. -Nr.: HY-N2001
CAS. Nr.: 344911-90-6
Category:  

Triterpenes other families Terpenoids Metabolic Disease Plants Disease Research Fields

Target:  

Others

Araloside X (Congmunoside X) is a triterpenoid saponin isolated from Aralia elata .
Asarinin
Asarinin
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Art. -Nr.: HY-N0701A
CAS. Nr.: 133-05-1
Category:  

Asarum sieboldii Miq. Lignans Phenylpropanoids Plants Disease Research Fields Aristolochiaceae Cancer

Target:  

Others

Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb .
Aralia-saponin I
Aralia-saponin I
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Art. -Nr.: HY-N15146
CAS. Nr.: 289649-54-3
Category:  

Triterpenes Terpenoids Plants Pentacyclic Triterpenoids Araliaceae Aralia chinensis L.

Target:  

Bacterial

Aralia-saponin I is a saponin that can be isolated from Aralia elata, possessing high binding affinity for aerolysin and capable of binding to amino acids critical for aerolysin function. Aralia-saponin I can be utilized in research on infections caused by Aeromonas hydrophila .
9-Methoxyaristolactam I
9-Methoxyaristolactam I
0 Images
Art. -Nr.: HY-N11529
CAS. Nr.: 133462-30-3
Category:  

Asarum sieboldii Miq. Alkaloids Pyrrole Alkaloids Plants Aristolochiaceae

Target:  

Others

9-Methoxyaristolactam I is a natural product that can be isolated from the roots of Asarum sieboldii Miq. var. Seoulense Nakai .
Ecliptasaponin B
Ecliptasaponin B
0 Images
Art. -Nr.: HY-N17978
CAS. Nr.: 185382-93-8
Category:  

Terpenoids Aralia elata (Miq.) Seem. Plants Pentacyclic Triterpenoids Araliaceae

Target:  

Drug Derivative

Ecliptasaponin B (compound 7) is a triterpenoid saponin and growth inhibitor present in the leaves of Aralia elata Seem.
MIQ-N-succinate
MIQ-N-succinate
0 Images
Art. -Nr.: HY-155442
CAS. Nr.: 1511896-15-3
Target:  

Biochemical Assay Reagents

Forschungsgebiete:  

Inflammation/Immunology

MIQ-N-succinate is a hapten with a four-carbon chain. MIQ-N-succinate consist of MIQ and succinic anhydride. MIQ-N-succinate has a carboxylic acid end group to attach to the lysine residues on the carrier proteins .
Prenylamine lactate
Prenylamine lactate
0 Images
Art. -Nr.: HY-A0257A
CAS. Nr.: 69-43-2
Target:  

CaMK

Forschungsgebiete:  

Neurological Disease

Prenylamine lactate is a calcium-modulating protein (CaM) antagonist that inhibits CaM-dependent enzymes and can slowly relax smooth muscle preparations. The effect of Prenylamine lactate on smooth muscle is not inhibited by the calcium agonist Bay K 8644 (HY-10588). Reports suggest that under low heart rate conditions, Prenylamine seems to enhance voltage-dependent transmembrane calcium currents .
Tarasaponin IV
Tarasaponin IV
0 Images
Art. -Nr.: HY-N9328
CAS. Nr.: 156980-31-3
Category:  

Triterpenes Terpenoids Plants Disease Research Fields Araliaceae Cancer Aralia chinensis L.

Target:  

Others

Tarasaponin IV, as an oleanane-type triterpene saponin, is isolated from the bark of Aralia elata. Tarasaponin IV can be used for the research of cancer .
Assay Types